Women’s Hormone Health — by Dr María Zalazar

Understanding women’s hormone health is essential at every age. Here you’ll find clear explanations and expert content about oestrogen, progesterone, testosterone, thyroid hormones and the conditions influenced by them — including perimenopause, menopause and more. All content is curated by Dr María Zalazar to help women navigate hormonal changes with clarity.

Natural progesterone side effects – genetics, metabolism and hormone response
How to Reduce the Side Effects of Natural Progesterone — and Why Some Women Tolerate It Better Than Others
Natural progesterone is usually the safest and most physiologically aligned option for midlife women. Yet some still experience dizziness, bloating or mood changes. These reactions are almost always related to how each woman absorbs and responds — not to the progesterone itself. Here, we look at the three key scientific reasons behind these symptoms and how to improve tolerance using evidence-based strategies.
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Thyroid dysfunction and menopause symptoms explained by Dr María Zalazar
Thyroid Dysfunction and Perimenopause — How to Tell the Difference
Thyroid disorders become more common between 40 and 60 — and their symptoms often overlap with perimenopause. Fatigue, mood changes, weight gain, anxiety, palpitations, irregular periods, constipation and sleep problems can come from low oestrogen, an underactive thyroid… or both at the same time.Here, we look at the key links between thyroid hormones and ovarian hormones, the most common thyroid disorders at midlife, and how to recognise the differences.
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low oestrogen after 40 - belly fat change
Why Low Oestrogen After 40 Causes Belly Fat, Weight Gain and Body Changes
In perimenopause and postmenopause, low oestrogen changes metabolism, increases visceral fat, and alters body composition — even without eating more. In this guide, Dr María Zalazar explains: what happens inside the body when oestrogen declines, the four main causes of these changes, why weight gain happens even with the same lifestyle, and the strategies that truly help.
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Lightbox showing “HRT hormone therapy” on a pink background, used for an article on the four approved indications for hormone replacement therapy
Menopause replacement therapy: the four approved indications and how to recognise them
Menopause replacement therapy (HRT) is the most effective treatment for symptoms and health risks caused by low oestrogen. This guide explains the four approved medical indications for HRT and how to recognise each one. We cover vasomotor symptoms, genitourinary syndrome of the menopause, osteoporosis prevention, and primary ovarian insufficiency.
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Illustration of a balance scale representing hormonal balance, progesterone effects, and weight stability in midlife women
Does Progesterone Cause Weight Gain?
Progesterone is used in perimenopause, premenstrual disorders, and endometriosis — each with different effects.. Many women wonder whether progesterone causes weight gain. In reality, its effects depend on the type used and the hormonal context — especially during perimenopause, menopause, endometriosis, or premenstrual disorders.
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Dr. Maria Zalazar working on menopause education on a computer, representing evidence-based medical guidance
Perimenopause & post-menopause: 3 Essential Pillars Every Woman Should Know
Perimenopause and post-menopause are not only about hot flushes. They involve metabolic, bone, cardiovascular and other systemic changes that often begin years before periods stop. Understanding these changes early—and the evidence-based options available—helps women make confident, informed decisions about long-term health.
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